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Ann Intern Med 173:278286 Overgaard RV, Navarria A, Ingwersen SH, Bkdal TA, Kildemoes RJ (2021) Clinical pharmacokinetics of oral semaglutide: analyses of data from clinical Pharmacology trials

Weeks 1-4: 2 to 3 mg daily

Nonetheless, current clinical practice in managing T2DM using GLP-1RAs is likely to vary worldwide due to differences in healthcare systems and their accessibility, in the availability and affordability of medications, as well as in country-specific reimbursement policies