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This is a type of anemia that is often distinguished by the lack of an intrinsic factor

This helps to maintain the effectiveness of the benzyl alcohol preservative and keeps the bac water shelf life at its maximum

Moreover, G289A and T337I mutations are located proximal to the ATP-binding pocket of the C-terminal domain, G289A would cause steric conflict with Ser293, and T337I would cause a hydrophobic patch on the protein surface and reduce protein solubility

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