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During wound healing, it can be removed from existing extracellular proteins by proteolysis and used as a chemical attractant for inflammatory and endothelial cells It can increase the production of messenger RNA in collagen, elastin, proteoglycans and glycosaminoglycans in fibroblasts

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Pharmacological management Pharmacological treatment has focused on prokinetic medications, but, as discussed, it is now appreciated that the relationship between symptomatic improvement and acceleration of gastric emptying is, at best, modest [68]

After 10 days, the number of wells containing spheres was determined for each condition and the software ELDA (Extreme limiting dilution analysis) was used to calculate the long-term cancer stem cell initiating frequency and significance [4]