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BPC-157 significantly reduced gastrointestinal bleeding and restored mucosal integrity in NSAID-induced ulcer models. Sikiric, P

Recent findings suggest that modifying AhR-dependent signaling in the intestine may diminish cholesterol absorption facilitated by the GI cholesterol transporter Niemann-Pick C1-like 1 by inhibiting the transcriptional function of sterol regulatory element-binding protein-2 34

This food effect can effectively double systemic drug exposure without changing the nominal dose an often-overlooked factor in safety discussions

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