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189 , 114122 (2015) Scheres, S

6b), the master mix containing 0.5 M YPEL5CTLH E3, 0.25 M FAMBRD4 BD1 and 1 M phosphorylated UBE2H was first prepared and then mixed with 10 M JQ1 or a given degrader derivative (at 2% final DMSO concentration)