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1 Adherence and Discontinuation Rates Despite their proven efficacy, adherence to GLP-1, dual, and triple agonist therapies in adolescents remains a challenge due to side effects, injection-related concerns, and long-term commitment issues

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If these treatments help address root causes such as metabolic dysfunction and inflammation, they could potentially have a positive impact on bipolar symptoms as well

Transient receptor potential channel 1 deficiency impairs host defense and proinflammatory responses to bacterial infection by regulating protein kinase C signaling