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Evidence from Pregnancy Studies and Extrapolation to Lactation GLP-1 use during pregnancy is generally not recommended due to limited fetal safety data, though no definitive teratogenic signal has emerged

This group frequently includes individuals managing nutrient malabsorption conditions such as Crohns disease or celiac disease, where the gastrointestinal tracts reduced capacity to absorb nutrients makes the intravenous route particularly practical from a clinical standpoint

In contrast, GLP-1 users often experience 4-6 pounds of monthly weight loss, fundamentally altering how the body responds to volume changes

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