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This phenomenon indicates that the diuretic and natriuretic effects of DPP-4i are mediated by preventing the degradation of GLP-1

[30]Kalinhoff C, Caldern NT

Proc Natl Acad Sci U S A 101:88412, PMID: 15187230 Into T, Inomata M, Nakashima M, Shibata K, Hcker H, Matsushita K (2008) Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses

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