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prescriptions are based on standard weight-loss eligibility and reported comorbidities

doi: 10.1210/jc.2019-00033 63 CaoCYangSZhouZ

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A common arc in practice uses an induction and titration phase (slowly working up to an effective dose), a maintenance phase while weight, labs, and habits stabilize, and for some a cautious dose reduction once lifestyle and body composition can shoulder more of the load. The goal is to build a metabolism, muscle base, and daily routine that can hold gains with less pharmacologic support over time when appropriate, rather than assuming everyone must stay on the highest dose indefinitely. How Safety and Monitoring Shape Long-Term Plans Any medication you may use for years needs a safety plan as detailed as the dosing plan