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Consequently, a decrease in BA levels lead to enhanced pro-inflammatory cytokine production and impaired polarization towards the M2 anti-inflammatory phenotype, thereby exacerbating inflammatory responses in gout ( Figure 2 )

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MPO ( R = 0.566, p = 0.044) and MMP-9 ( R = 0.441, p = 0.05) were negatively correlated and TIMP-1 ( R = 0.367, p = 0.089) was marginally positively correlated with duration of PTSD illness (see Figure 3)