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AMPK also inhibits lipid biosynthesis by suppressing transcription factor sterol regulatory element-binding protein 1 (SREBP1) and promoting the action of peroxisome proliferator-activated receptor alpha (PPAR), a nuclear receptor that acts to enhance both mitochondrial and peroxisomal FA -oxidation 23

Therefore, GSH production in sample 6, which contain lower ATP, might be hindered by the detection limit

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IV glutathione injections could be more effective since they are introduced directly into the circulation, but they also pose more dangers and are not approved for skin whitening in many countries