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C.IliopoulosO.MierJ

Active LPL then enters the Golgi, where sortilin-related receptor with type-A repeats (SorLA) chaperones LPL through further post-translational modifications, sorting, and secretion, where LPL is tethered to heparan sulfate-proteoglycans (HSPG) on the cell surface (10)

We typically put our patients on weekly injections for a minimum of 12 weeks, or three months of treatment

Therefore, we speculated that T cells could induce microglial polarization through direct contact, cytokine-mediated communication or antigen presentation, thereby amplifying their impact on the cerebral immune milieu