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Some earlier analyses raised concern that a notable portion of weight lost may be lean mass, although newer reporting suggests the muscle-loss story is more nuanced and may include changes in liver size, water, and other lean tissues, not only skeletal muscle

In addition, Pycnogenol increased the total antioxidant status (TAS) and improved the glutathione levels, another index for antioxidant capacity in the children with ADHD ( administration, while reduced glutathione (GSH) was significantly increased by 26.8% after one month and by 36.4% after 2 months compared to baseline ( s effects on ADHD symptoms by improving the antioxidant status