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While gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation) affect many patients initially, severe or persistent symptoms may necessitate dose adjustment, temporary dose reduction, or consideration of alternative therapies

Weight loss achieved before pregnancy often provides metabolic benefits that persist even after the medication is stopped

All patients stopped taking psoriasis medication four weeks before beginning heliotherapy

The use of DBS for screening has several advantages over screening in plasma: only a minor amount of blood is required, and it can be easily collected, shipped and stored