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Knockdown of FOXM1, and IRF-8, and inhibition of BRD4 using JQ1, an antagonist of BRD4, suppressed the production of inflammatory cytokines, inflammatory mediators, and MMPs, including MMP-3, -9, and -13, shown in Figure 1

In rats, they triggered stomach ulcers three different ways with stress, with a chemical called cysteamine, and with almost pure alcohol

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