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These adverse events lead some patients to discontinue therapy before achieving optimal clinical outcomes, reducing long-term treatment adherence

Pinhas-Hamiel O, Zeitler P

Perfil de Seguridad Retatrutida y Mounjaro tienen perfiles de seguridad similares

While Ser2 of oxyntomodulin and Ala8 of GLP-1 both interacted with TM7 residues, these interactions were stronger with oxyntomodulin due to a persistent hydrogen bond between Ser2 and E387 7 .42 and transient hydrogen bonds and van der Waals contacts with K383 7 .38 , D372 ECL3 and L384 7 .39 (Supplemental Table 3)