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In two Phase 3 trials (SURMOUNT-OSA 1 & 2), tirzepatide (Mounjaro) a dual GIP/GLP-1 receptor agonist reduced the severity of obstructive sleep apnea (OSA) by up to 63% after 52 weeks

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Tirzepatide is an active ingredient that targets two hormone receptors, GLP-1 and GIP, to reduce appetite, support blood sugar regulation, and promote weight loss

Although there is sound biologic rationale based on experimental data that glutamine contributes to the synthesis of GSH, its relative importance compared to other amino acids such as -ketoglutarate and L-cysteine has not been established, especially in SCD