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Weight-based dosing considerations While the standard clinical trial protocols use fixed-dose titration schedules regardless of body weight, some researchers adjust their approach based on body composition

Studies on mice indicated that this could be countered by introducing bacteria into the gut that have the opposite effect, such as Lactobacillus rhamnosus , Lactobacillus acidophilus , and Bifidobacterium bifidum

For example if a patient loves chocolate but it doesnt fill them up, advise them to swap it for low-calorie ice cream. Tools such as a food tracker app might also help patients regain a sense of control as they see their intake coming down

I had no way to test that idea, but the question never left me