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Active efflux transporter, PgP, solute carrier transporters, OATs, and carrier-mediated transporters, MCT8 and LAT1, and the receptor-mediated transporter, LRP-1, decrease in activity, mRNA expression, or protein expression are also reduced following LPS challenge [67, 72,73,74,75]

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What the evidence suggests: dermatological observations have noted skin-brightening effects, particularly in hyperpigmentation, melasma, and post-inflammatory darkening

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