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Same BMI, same medical need, different zip code, different outcome

GLP-1RAs replicate the activity of the endogenous incretin hormone GLP-1, which is secreted by the gut in response to food intake

Direct effects on cellular proliferation A genetically engineered murine model of pancreatic intraepithelial neoplasia (PanIN) to PDAC progression ( LSL-Kras G12D ;Pdx1-Cre, KC ) treated with exenatide demonstrated architectural changes of loss of polarity and micropapillary formation following 12 weeks of therapy 18

Introduction Despite major advance in treatment, cardiovascular diseases are still one of the leading causes of mortality and morbidity in the world