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Proc Natl Acad Sci USA 95:492498 Wang Z, Cao H, Sun Y, Li X, Chen F, Carles A, Li Y, Ding M, Zhang C, Deng X et al (2013) Arabidopsis paired amphipathic helix proteins SNL1 and SNL2 redundantly regulate primary seed dormancy via abscisic acidethylene antagonism mediated by histone deacetylation

Caffeine is well known for increasing energy expenditure and fat oxidation

10.1093/nar/gkab1061 171 WangH.AvillachP

While alternative administration routes, such as intravenous, intramuscular, nasal, percutaneous, and transdermal delivery, have shown promise in certain conditions, these methods can be invasive and uncomfortable for patients