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The prevalence of hypertension among individuals aged 30-79 years doubled from 648 million people to 1278 million people between 1990 and 2019 (Zhou et al., 2021)

By supporting significant weight loss, it addresses one of the root causes of GERD rather than just managing the symptoms

Physiology (Bethesda) 2004

the FDA also notes these reports are likely underreported because state-licensed 503A pharmacies are generally not required to submit adverse events to FDA