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Changes to insulin or oral agents might be required as the effect of GLP-1 and intraoperative glucose shifts can cause unanticipated hypoglycemia or hyperglycemia

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On a side note: If a patient plans pregnancy, it is recommended to stop using Ozempic (Semaglutide) 2 mg/1.5 ml in advance

The difference in total weight loss was also striking: after about two years, the surgical patients had lost an average of 28.3% of their starting body weight, while those treated with GLP-1s lost an average of 10.3%