After weeks of nausea, vomiting, and sharp abdominal pain, doctors found a large, stubborn mass in her stomach a gastric bezoar that was likely tied to her semaglutide (the same active ingredient thats in Ozempic and Wegovy).Instead of surgery, her doctors treated it with something youd never expect: 1.5 liters of Diet Coke, which dissolved the mass in a matter of days!Published in the New England Journal of Medicine, this unusual case has people not only talking about the rare but serious stomach risks that come with certain weight-loss drugs, but also about how something like Diet Coke, which is considered unhealthy for many reasons, can become a saviour in certain situations
Some patients report that it takes an extra hour or two to feel the effects of their oral medications once they begin a GLP-1 program
Specifically, in-house donors exhibited lower NAD + , NADH and NADP + levels (on average 3.2, 0.47 and 1.6 uM lower, respectively) but higher NADPH levels (on average 0.88 uM) compared to biobank samples (Supplementary Figure 2a)
In a recent 1 year trial by Hansen et al