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Johnson, B., Milstead, M., Thomas, O., McGlasson, T., Green, L., Kreider, R., & Jones, R

Therefore, Y1R agonists and Y2R antagonists (since Y2R acts as an autoreceptor) seem promising for the treatment of heavy drinking that is driven by anxiety or negative reinforcement

The antihypertensive activity of OS is due to its vasodilator and diuretic activities, the latter probably due to its binding with the renal adenosine A1 receptor (135)