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In research, the effect of melatonin on the sensitivity of 5-FU was investigated

Next, the mitochondrial fuel dependency tests were performed in the vector and the SIRT3OE adipocytes, achieved by co-treatment of inhibitors of mitochondrial pyruvate carrier (glucose oxidation pathway), glutaminase (glutamine oxidation pathway) and CPT1 (FAO pathway) successively

It has been declared, that neurotoxic 6-hydroxydopamine (and also superoxide radical) is able to release free iron from ferritin which in turn may participate in Fenton chemistry, forming ROS and initiating lipid peroxidation (Monteiro and Winterbourn 1989)

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