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Studies have demonstrated that GLP-1RAs exert a direct effect on the heart and blood vessels (6) and an indirect effect via improved glycaemia (24), a reduction in blood pressure and postprandial rise in triglycerides (25), a reduction in markers of oxidative stress and systemic inflammation (26, 27) (Fig
After screening by title and abstract, 16 articles were available to be assessed in full-text screening
The news dropped as the cost and demand for GLP-1s was one of the dominant topics at the 2024 AHIP conference, with industry leaders expressing concern about the high price tags for many of these drugs even as questions remain about the long-term efficacy and impacts on patients
Researchers interested in this direction can see more details on the efficacy of GLP-1R/GCGR agonists in the treatment of obesity in Sanchez-Garridos review (131)
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