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MICC (Methionine, Inositol, Choline, Cyanocobalamin) MICC is a compounded blend of four nutrients: methionine, inositol, choline and cyanocobalamin (a form of vitamin B12)
In this sense, several diseases or conditions or genetic disorders that are predisposing to eryptosis, including deficiency in glucose-6-phosphate dehydrogenase, sickle cell anemia, beta-thalassemia trait, iron insufficiency or deficiency of carriers like GLUT1, AE1 are known to provide a certain degree of defense against a severe malarial course [230, 404]
Thus, reducing insulin resistance is an efficient approach in these patients (Reference Carmina and Azziz17)