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Obesity is more complicated than a simple imbalance of the hormone mimicked by these drugs, but doctors do now generally consider it a chronic disease

Diese Eigenschaft war der Grund dafr, dass die Wirkstoffe ursprnglich zur Behandlung von Typ-2-Diabetes entwickelt wurden

Previous work has shown that the clock regulates NAD + biosynthesis and deacetylation pathways that, in turn, regulate mitochondrial enzyme activity 4,35