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Maintaining an adequate GSH redox status and 25-hydroxy-vitamin D levels will have the potential to reduce oxidative stress, enhance immunity and diminish the adverse clinical consequences of COVID-19 especially in African American communities having glucose-6-phosphate dehydrogenase (G6PD) deficiency, enzyme necessary to prevent GSH exhaustion and depletion (213, 310)

Initial studies demonstrated that, in mild C-19 cases, patients might have had stronger local immunity and the virus replicated in the mucosa (76)

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