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Elevated medium-chain acylcarnitines in this group mirrored those seen in the TB cohort, hinting at increased fatty acid oxidation possibly linked to dysfunctional mitochondrial respiration often associated with diabetes

Notably, once a patient transitions to combination injectable therapy, the ADA recommends the addition of a GLP-1 receptor agonist for patients who require improved postprandial glycemic control despite basal insulin optimization

It addresses the most common challenge GLP-1 and GLP-1/GIP patients face: gastrointestinal side effects

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