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Included were adults with type 2 diabetes taking semaglutide, other GLP-1 drugs (dulaglutide, exenatide) or non-GLP-1 receptor medications (empagliflozin, sitagliptin, glipizide) from December 2017 to December 2023

pathway failure drives iron accumulation, HIF1 stabilization, inflammasome activation, and tumor progression

Moreover, it is implicated in the pathophysiology of metabolic, cardiovascular, and malignant diseases [149]