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These findings highlight tirzepatide's potential to revolutionize treatment for high-risk T2DM patients, offering not only improved metabolic control but also a favorable cardiovascular safety profile [71]

Questions Did you learn something you didnt know before about GLP-1 medications

Semaglutide is FDA-approved for long-term or chronic weight management in obese patients with a body mass index (BMI) of 30 or greater or overweight patients with a BMI of 27 or greater with at least one weight-related condition such as type 2 diabetes, high blood pressure, high cholesterol, or others

Genetic variants in GLP1R (rs6923761) and GIPR (rs1800437) influence receptor sensitivity and trafficking