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Quantitative analysis of IHC human post-mortem brain sections Scanned human brain sections were analysed by ImageScope where the image was split into four separate colour channels (blue: negative, yellow: weakly positive, orange: moderately positive and red: strongly positive pixels)

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Independently of this -MSH/MC1R pathway, PGE 2 can promote tyrosinase activity and arborisation of melanocytic dendrites