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Using the clinically-validated 176.5mg dose shows a commitment to evidence-based formulation rather than just marketing hype
However, neither BAL fluid nor intracellular GSH, GSSG, and GSH:GSSG correlated with BAL eosinophils or any other inflammatory cell, suggesting eosinophilia plays a lesser role in contributing to higher extracellular/BAL fluid GSSG than epithelial cells do (Supplemental Tables 3 and 4)
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Functionally, the main compounds (emodin, rhein, baicalin, and chrysin) from Chaiqin chengqi decoction diminished pancreatic acinar cell necrosis and systemic inflammation by inhibiting the TLR4/NLRP3 pathway ( Qingyi decoction and its active ingredients (e.g., Wogonoside) alleviated pancreatic injury and systemic inflammation in AP by inactivation of the NF-B/NLRP3/Caspase-1 pathway (Zhang R
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