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Cancer Chemother Pharmacol (2020) 86(1):5563

Although originally intended for individuals with type 2 diabetes, metformin has proven effective in pregnancy programsespecially for women with PCOS or obesity

Zileuton, an anti-inflammatory compound, inhibits LOX5 and decreases -secretase, A, and tau after three months of treatment in a 3xTg mouse AD model (Di Meco et al., 2014), demonstrating its broad prospects for clinical use