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In addition, MYC, a transcription factor that improves sensitivity to apoptosis stimulation, is upregulated, along with the activation of other apoptotic pathways, 26,124,125 causing irreversible damage or even death of cells
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The authors reported a 39% improvement in the TWSTRS (i.e., Toronto Western Spasmodic Torticollis Rating Scale) score and a 40% improvement in the quality of life questionnaires from one toxin injection to the other (12 weeks, 20 mixed-site stimulation sessions) without any other neurophysiological change
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