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These technologies may accelerate the discovery of novel therapeutic targets and the development of personalized regimens, serving as critical cutting-edge tools to advance autophagy-ferroptosis-targeted therapy from basic research to clinical translation

In mammals, ferroptosis has been implicated in diverse pathologies, including neurodegenerative diseases, stroke, traumatic brain injury and kidney degeneration, as well as in carcinogenesis, where it may exert a tumor-suppressor function

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