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AOPP levels increase in response to oxidative stress and can serve as markers of protein damage and inflammation in CLDs [74]

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Summary of Key Amylin-Based Therapies in Development (April 2026) Cagrilintide is a long-acting amylin analogue under investigation for obesity management, and the combination of cagrilintide with semaglutide (CagriSema) has demonstrated superior weight loss and metabolic benefits compared with either agent alone or placebo in recent clinical trials