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It is a systemic intervention that happens to have effects in the exact pathways that drive migraine

RG participated in the design, coordination of the study and finalized the manuscript

People with lower natural production of lactase, alpha-galactosidase, or other digestive enzymes are more susceptible to fermentation-related gas because they incompletely digest certain food components

123 Besides, synaptic plasticity-related proteins, including CREB, pCREB, brain-derived neurotrophic factor (BDNF), and activity-regulated cytoskeleton (Arc) proteins, are significantly reduced