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The most common side effects reported to date have been malnourishment, due to a dramatic reduction in calorie intake, and significant gastrointestinal symptoms

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This work confirmed that the lizard species' unique genes produce a protein, Exendin-4, that fit the bill, mimicking GLP-1 while hanging round in the human body for far longer

Relationship to expression profiles in other COPD studies In order to show that the gene expression signature of regional emphysema severity is present in larger cohorts of patients with earlier stages of disease, we used GSEA to examine the relationship between genes associated with regional emphysema severity in this dataset and genes associated with COPD phenotypes in other cross-sectional studies [611]