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Also, GSH status was measured in the fasting state only, defined by the protocol as at least a 12-hour, overnight fast, further reducing possible sources of variability

The trade-off is a very short half-life of approximately 20-30 minutes after subcutaneous injection, making it unsuitable for systemic use and largely studied in local tissue applications [10]

The available data indicate the following potential effects of synthetic TB4 (TB-500): TB-500 may help the healing of the eye cornea, as noted in a 28-day phase-2 study in nine patients with severe dry eye

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