The metyrapone test was performed in 18 methadone-maintained former heroin addict patients, 10 without and 8 with ongoing cocaine dependence, resulting in ACTH hyperresponsivity in the latter group (78)
An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]
Cerebrolysins trial base is heavily Russian, Chinese, and Eastern European, several studies were manufacturer-supported, and that concentration is exactly the kind of thing that inflates apparent benefit
Benefits of Glutathione Infusions Lightens skin tone Helps reduce dark spots Helps prevent/remove acne and acne scars Powerful anti-aging and anti-wrinkle effect Skin is smoother and more radiant Improves the healing process on skin wounds and blemishes Nourishes the skin Promotes overall health Unlike oral supplementation, glutathione infusions immediately raise glutathione levels in the body making it more effective and offering faster results