glp 1 weight loss percentage The of U.S. adults who currently take GLP-1 medications for purposes has risen to 11% in 2026, up significantly from 3% in 2024. And 15% report having used the Glucagon-like peptide-1 (GLP-1) receptor agonist

What the research shows about GLP-1 medications: According to a study published in the New England Journal of Medicine (STEP-1 trial), participants receiving once-weekly semaglutide 2.4 mg plus lifestyle intervention experienced a mean weight loss of 14.9% from baseline over 68 weeks, compared with 2.4% for placebo plus lifestyle intervention

Greenamyre JT, Cannon JR, Drolet R, Mastroberardino PG

Dont Ignore the Urge Holding in bowel movements can make stool harder and more difficult to pass later

[of importance] o This case report is among the first to document probiotic-associated brain fog, suggesting a gutbrain axis mechanism linking gastrointestinal dysbiosis to cognitive symptoms