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Avoid the all-or-nothing trap that leads to burnout (you know the onewildly ambitious Monday through Wednesday, then nothing until the following month)

When using dilute acetic acid (0.1% v/v) as a solvent, it can improve initial solubilization of certain peptide batches, but the solution pH should be adjusted to near-physiological range before administration to avoid tissue irritation at the injection site in animal models

We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)

For a deeper understanding of this transition, see our guide on peptide reconstitution principles