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qRT-PCR analysis revealed the marked upregulation of CDKN2A (encoding p16) , CDKN1A (encoding p21) , interleukin-8 ( IL-8) , and matrix metalloproteinase ( MMP)-12 expression (Figure 1D)

This provides evidence for reducing excessive autophagy in ovarian granulosa cells and improving PCOS symptoms

To date, it has been used in multiple cell lines such as cervical cancer, glioma, thyroid cancer, renal cancer, bladder cancer and gastric cancer cells.In cervical cancer research, treatment of HeLa cervical cancer cells with the product significantly inhibits cancer cell proliferation in a concentration and timedependent manner

Cancer 16 (10), 749634