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INDICACIONES Y ADVERTENCIAS: No se recomienda su uso durante el embarazo y la lactancia

doi: 10.1507/endocrj.EJ21-0486 20 KwakMJ

Primary Causes (Testicular) Age-related decline (starting around 30) Testicular injury or infection Cancer treatment (chemo, radiation) Genetic conditions (Klinefelter syndrome) Undescended testicles Secondary Causes (Brain/Pituitary) Chronic stress (elevated cortisol) Obesity (fat converts T to estrogen) Poor sleep / sleep apnea Pituitary disorders Medications (opioids, steroids) Low Testosterone in Men Over 40 Testosterone levels naturally decline about 1% per year after age 30

As such, suboptimal medication adherence and access can underestimate long-term ASCVD risk reduction correlates associated with GLP-1RA therapy