selenium and glutathione peroxidase Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis inflammatory effects. Plasma levels of selenium, selenoprotein

Key functions of glutathione include: Neutralizing free radicals and reactive oxygen species directly Supporting the regeneration of other antioxidants like vitamins C and E Assisting in detoxification of harmful compounds in the liver Supporting immune system function Maintaining cellular health and protein synthesis Protecting mitochondria (the energy centers of cells) Despite its importance, glutathione levels naturally decline with age

Ford ES, Cunningham TJ, Giles WH, Croft JB

Behavioral profile of vitamin B(12) deficiency: a reflection of impaired brain development, neuronal stress and altered neuroplasticity

Trends Mol Med (2019) 25(2):11223