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Studies in humans show an enhanced expression of -defensin genes in colonic inflammations [185]

Broder I, Higgins MW, Mathews KP, & Keller JB (1974a) Epidemiology of asthma and allergic rhinitis in a total community, Tecumseh, Michigan

Phase 3 TRIUMPH-4 trial The most recent Phase 3 results, announced in December 2025, tested retatrutide in people with obesity and knee osteoarthritis