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Future studies must better define the molecular context of antioxidant action, including the following: which biomolecules are being protected, the specific radical species targeted, the tissue and subcellular distribution of the antioxidant, and how levels of endogenous antioxidants and reactive oxygen species (ROS) change post-administration (e.g., within the mitochondria)

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Because none of them tested enemas, whether they are more effective than oral coffee (or effective at all) remains unknown [21, 22, 23]

Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase cdelta